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Regulation of hBD-2, hBD-3, hCAP18/LL37, and Proinflammatory Cytokine Secretion by Human Milk Oligosaccharides in an Organotypic Oral Mucosal Model

Human milk oligosaccharides (HMOs), the third largest solid fraction in human milk, can modulate inflammation through Toll-like receptor signaling, but little is known about their immunomodulatory potential in the oral cavity. In this study, we determined whether the HMOs 2′-fucosyllactose (2′-FL) a...

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Principais autores: Ulvi K. Gürsoy, Krista Salli, Eva Söderling, Mervi Gürsoy, Johanna Hirvonen, Arthur C. Ouwehand
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-06-01
Serier:Pathogens
Fag:
2′-fucosyllactose
3-fucosyllactose
human beta defensins
cathelicidin
oral mucosal model
Online adgang:https://www.mdpi.com/2076-0817/10/6/739
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