TLR4 modulates inflammatory gene targets in the retina during Bacillus cereus endophthalmitis

Abstract Background Endophthalmitis is a serious intraocular infection that frequently results in significant inflammation and vision loss. Because current therapeutics are often unsuccessful in mitigating damaging inflammation during endophthalmitis, more rational targets are needed. Toll-like rece...

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Autors principals:	Phillip S. Coburn, Frederick C. Miller, Austin L. LaGrow, Salai Madhumathi Parkunan, C. Blake Randall, Rachel L. Staats, Michelle C. Callegan
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2018-04-01
Col·lecció:	BMC Ophthalmology
Matèries:	Bacterial endophthalmitis Retinal gene expression Toll-like receptor 4 Gram-positive intraocular infections
Accés en línia:	http://link.springer.com/article/10.1186/s12886-018-0764-8
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