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Computational Methodologies for the in vitro and in situ Quantification of Neutrophil Extracellular Traps

Neutrophil extracellular traps (NETs) are a neutrophil defensive mechanism where chromatin is expelled together with antimicrobial proteins in response to a number of stimuli. Even though beneficial in many cases, their dysfunction has been implicated in many diseases, such as rheumatoid arthritis a...

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Principais autores: Shane V. van Breda, Lenka Vokalova, Claire Neugebauer, Simona W. Rossi, Sinuhe Hahn, Paul Hasler
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-07-01
Serier:Frontiers in Immunology
Fag:
neutrophil extracellular traps
myeloperoxidase
neutrophil elastase
citrullinated histone
machine-learning
Online adgang:https://www.frontiersin.org/article/10.3389/fimmu.2019.01562/full
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