Myt1l haploinsufficiency leads to obesity and multifaceted behavioral alterations in mice

Abstract Background The zinc finger domain containing transcription factor Myt1l is tightly associated with neuronal identity and is the only transcription factor known that is both neuron-specific and expressed in all neuronal subtypes. We identified Myt1l as a powerful reprogramming factor that, i...

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Autors principals:	Markus Wöhr, Wendy M. Fong, Justyna A. Janas, Moritz Mall, Christian Thome, Madhuri Vangipuram, Lingjun Meng, Thomas C. Südhof, Marius Wernig
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-05-01
Col·lecció:	Molecular Autism
Matèries:	Transcription factor Autism Obesity Social behavior Ultrasonic vocalization
Accés en línia:	https://doi.org/10.1186/s13229-022-00497-3
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