Multi-trait association analysis reveals shared genetic loci between Alzheimer’s disease and cardiovascular traits

Abstract Several cardiovascular traits and diseases co-occur with Alzheimer’s disease. We mapped their shared genetic architecture using multi-trait genome-wide association studies. Subsequent fine-mapping and colocalisation highlighted 16 genetic loci associated with both Alzheimer’s and cardiovasc...

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Detalhes bibliográficos

Principais autores:	Fotios Koskeridis, Nurun Fancy, Pei Fang Tan, Devendra Meena, Evangelos Evangelou, Paul Elliott, Dennis Wang, Paul M. Matthews, Abbas Dehghan, Ioanna Tzoulaki
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-11-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-024-53452-6
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