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A generic approach to study the kinetics of liquid–liquid phase separation under near-native conditions

Van Lindt, Bratek-Skicki et al. show that at carefully selected pH values, proteins can be kept in solution and their LLPS can then be induced by a jump to native pH. This presents a generic method to study the full kinetic trajectory of LLPS under near native conditions that can be easily controlle...

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Autors principals: Joris Van Lindt, Anna Bratek-Skicki, Phuong N. Nguyen, Donya Pakravan, Luis F. Durán-Armenta, Agnes Tantos, Rita Pancsa, Ludo Van Den Bosch, Dominique Maes, Peter Tompa
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2021-01-01
Col·lecció:Communications Biology
Accés en línia:https://doi.org/10.1038/s42003-020-01596-8
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