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Discovery and replication of gene influences on brain structure using LASSO regression

We implemented LASSO (least absolute shrinkage and selection operator) regression to evaluate gene effects in genome-wide association studies (GWAS) of brain images, using an MRI-derived temporal lobe volume measure from 729 subjects scanned as part of the Alzheimer’s Disease Neuroimaging Initiative...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Omid eKohannim, Derrek P Hibar, Jason L Stein, Neda eJahanshad, Xue eHua, Priya eRajagopalan, Art eToga, Clifford R Jack Jr, Michael W Weiner, Greig I de Zubicaray, Katie L McMahon, Narelle K Hansell, Nicholas G Martin, Margaret J Wright, Paul M Thompson
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2012-08-01
Rangatū:Frontiers in Neuroscience
Ngā marau:
Neuroimaging
GWAS
MRI
imaging genetics
LASSO
MACROD2
Urunga tuihono:http://journal.frontiersin.org/Journal/10.3389/fnins.2012.00115/full
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