Low HDL cholesterol and the eNOS Glu298Asp polymorphism are associated with inducible myocardial ischemia in patients with suspected stable coronary artery disease

Abstract Background The endothelial nitric oxide synthase (eNOS) gene deficiency is known to cause impaired coronary vasodilating capability in animal models. In the general clinical population, the eNOS gene polymorphisms, able to affect eNOS activity, were associated with cardiometabolic risk feat...

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Detalhes bibliográficos

Principais autores:	Cecilia Vecoli, Chiara Caselli, Martina Modena, Giancarlo Todiere, Rosa Poddighe, Serafina Valente, Fabrizio Bandini, Andrea Natali, Lorenzo Ghiadoni, Aldo Clerico, Concetta Prontera, Simona Vittorini, Nicoletta Botto, Michele Emdin, Danilo Neglia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-03-01
coleção:	BMC Cardiovascular Disorders
Assuntos:	Endothelial dysfunction Endothelial nitric oxide synthase eNOS Single nucleotide polymorphism Obstructive coronary artery disease Inducible myocardial ischemia
Acesso em linha:	https://doi.org/10.1186/s12872-024-03846-7
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