The gasdermins: a pore-forming protein family expressed in the epidermis

Gasdermins comprise a family of pore-forming proteins, which play critical roles in (auto)inflammatory diseases and cancer. They are expressed as self-inhibited precursor proteins consisting of an aminoterminal cytotoxic effector domain (NT-GSDM) and a carboxyterminal inhibitor domain (GSDM-CT) sepa...

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מידע ביבליוגרפי

Principais autores:	Marta Slaufova, Tugay Karakaya, Michela Di Filippo, Paulina Hennig, Hans-Dietmar Beer
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2023-09-01
סדרה:	Frontiers in Immunology
נושאים:	gasdermin (GSDM) pyroptosis inflammasome skin interleukin - 1
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1254150/full
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