3D4 cells exhibit transcriptional features inconsistent with alveolar macrophage identity

Abstract The 3D4 cell lines are widely used as porcine alveolar macrophage models in immunological research. However, our preliminary experiments revealed that 3D4/21 cells failed to respond to lipopolysaccharide stimulation. We challenged both 3D4/21 and 3D4/2 clones with various Toll-like receptor...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Wenjuan Ma, Frieder Hadlich, Nares Trakooljul, Klaus Wimmers, Eduard Murani
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-10-01
Edice:	Veterinary Research
Témata:	Porcine alveolar macrophages 3D4 cell lines lipopolysaccharide immunometabolism transcriptome Toll-like receptor
On-line přístup:	https://doi.org/10.1186/s13567-025-01638-1
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!