Development of a Novel Alginate-Based Amlodipine Nanoplex for the Formulation of an Oral Film in Antihypertensive Therapy

<b>Background/Objectives:</b> Amlodipine is an antihypertensive agent characterized by low aqueous solubility and variable oral bioavailability. This study aimed to formulate and characterize amlodipine–alginate nanoplexes and to incorporate the optimized system into an oral film dosage form. <b>Met...

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Detalhes bibliográficos

Principais autores:	Javiera Medina, Thamara Hidalgo, Fabián Martínez, María Elena Gamboa-Arancibia, Néstor Gutiérrez-Sánchez, Sebastián Miranda-Rojas, Alexander Gamboa
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-05-01
coleção:	Pharmaceutics
Assuntos:	alginate nanoplexes amlodipine oral film polyelectrolyte–drug interactions amorphous solid state
Acesso em linha:	https://www.mdpi.com/1999-4923/18/6/653
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