Atroposelective Synthesis of Biaryl N‐Oxides via Cu‐Catalyzed De Novo Heteroaromatic N‐Oxide Ring Formation

Abstract Heteroaromatic N‐oxides, renowned for their highly polar N─O bond and robust structure, exhibit significant bioactivities and have played a pivotal role in various drug development projects since the discovery of Minoxidil. Moreover, heteroaromatic N‐oxides, featuring axially chiral biaryl...

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Hlavní autoři:	Ke Ma, Ting Qi, Lei Hu, Chen Chen, Wan Wang, Jun‐Long Li, Cheng Peng, Gu Zhan, Bo Han
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2024-10-01
Edice:	Advanced Science
Témata:	asymmetric catalysis atroposelective synthesis axially chiral heteroaromatic N‐oxide lewis base catalyst pyridine‐N‐oxide
On-line přístup:	https://doi.org/10.1002/advs.202405743
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