The Subcellular Distribution of Ryanodine Receptors and L-Type Ca2+ Channels Modulates Ca2+-Transient Properties and Spontaneous Ca2+-Release Events in Atrial Cardiomyocytes

Spontaneous Ca2+-release events (SCaEs) from the sarcoplasmic reticulum play crucial roles in the initiation of cardiac arrhythmias by promoting triggered activity. However, the subcellular determinants of these SCaEs remain incompletely understood. Structural differences between atrial and ventricu...

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Hlavní autoři:	Henry Sutanto, Bart van Sloun, Patrick Schönleitner, Marc A. M. J. van Zandvoort, Gudrun Antoons, Jordi Heijman
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2018-08-01
Edice:	Frontiers in Physiology
Témata:	calcium sarcoplasmic reticulum ryanodine receptor spontaneous calcium releases atrial fibrillation subcellular distribution
On-line přístup:	https://www.frontiersin.org/article/10.3389/fphys.2018.01108/full
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