Investigating Overlapping Genetic Factors and Novel Causal Genes in Autoimmune Diseases: A Transcriptome-Wide Association and Multiomics Study

Conclusion: This study uncovers shared genetic factors across five autoimmune diseases, with FLOT1 identified as a novel causal risk gene for SLE. These findings suggest that platelet-mediated pathogenic mechanisms may contribute to SLE, providing a potential target for future therapeutic interventi...

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Hlavní autoři:	Leihua Fu, Jieni Yu, Xin Wang, Zhe Chen, Jiaying Sun, Feidan Gao, Zhijian Zhang, Jiaping Fu, Pan Hong, Weiying Feng
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2025-01-01
Edice:	International Journal of Genomics
On-line přístup:	http://dx.doi.org/10.1155/ijog/9595651
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