Scavenging Intracellular ROS Attenuates <i>p</i>-Cresyl Sulfate-Triggered Osteogenesis through MAPK Signaling Pathway and NF-κB Activation in Human Arterial Smooth Muscle Cells

Osteogenesis in human arterial smooth muscle cell (HASMC) is a key feature of uremic vascular calcification (UVC). Concerning pro-oxidant properties of <i>p</i>-cresyl sulfate (PCS), the therapeutic effect of reactive oxygen species (ROS) scavenger on PCS triggered inflammatory signaling transductio...

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Detalhes bibliográficos

Principais autores:	Jia-Feng Chang, Chih-Yu Hsieh, Jian-Chiun Liou, Shih-Hao Liu, Chi-Feng Hung, Kuo-Cheng Lu, Chih-Cheng Lin, Chang-Chin Wu, Shuk-Man Ka, Li-Li Wen, Mai-Szu Wu, Cai-Mei Zheng, Wen-Chin Ko
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-07-01
coleção:	Toxins
Assuntos:	alkaline phosphatase c-Jun N-terminal kinase extracellular signal-regulated kinase mitogen-activated protein kinase nuclear factor-κB osteogenesis
Acesso em linha:	https://www.mdpi.com/2072-6651/12/8/472
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