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Doxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in lymphatic filariasis.

Lymphatic filariasis is a disease of considerable socioeconomic burden in the tropics. Presently used antifilarial drugs are able to strongly reduce transmission and will thus ultimately lower the burden of morbidity associated with the infection, however, a chemotherapeutic principle that directly...

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Principais autores: Alexander Yaw Debrah, Sabine Mand, Sabine Specht, Yeboah Marfo-Debrekyei, Linda Batsa, Kenneth Pfarr, John Larbi, Bernard Lawson, Mark Taylor, Ohene Adjei, Achim Hoerauf
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2006-09-01
Serier:PLoS Pathogens
Online adgang:https://doi.org/10.1371/journal.ppat.0020092
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