Identification of a large anion channel required for digestive vacuole acidification and amino acid export in Plasmodium falciparum.
Malaria parasites survive in human erythrocytes by importing and digesting hemoglobin within a specialized organelle, the digestive vacuole (DV). Although chloroquine and other antimalarials act within the DV, the routes used by drugs, ions, and amino acids to cross the DV membrane remain poorly und...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2025-05-01
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| Col·lecció: | PLoS Biology |
| Accés en línia: | https://doi.org/10.1371/journal.pbio.3003202 |
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