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Host M-CSF induced gene expression drives changes in susceptible and resistant mice-derived BMdMs upon Leishmania major infection

Leishmaniases are a group of diseases with different clinical manifestations. Macrophage-Leishmania interactions are central to the course of the infection. The outcome of the disease depends not only on the pathogenicity and virulence of the parasite, but also on the activation state, the genetic b...

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Principais autores: Cyrine Bouabid, Sameh Rabhi, Kristina Thedinga, Gal Barel, Hedia Tnani, Imen Rabhi, Alia Benkahla, Ralf Herwig, Lamia Guizani-Tabbane
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-04-01
Serier:Frontiers in Immunology
Fag:
macrophages
M-CSF
host background
Resistance
susceptibility
transcriptome
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1111072/full
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