Nernst–Planck–Gaussian finite element modelling of Ca2+ electrodiffusion in amphibian striated muscle transverse tubule–sarcoplasmic reticular triadic junctional domains

IntroductionIntracellular Ca2+ signalling regulates membrane permeabilities, enzyme activity, and gene transcription amongst other functions. Large transmembrane Ca2+ electrochemical gradients and low diffusibility between cell compartments potentially generate short-lived, localised, high-[Ca2+] mi...

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Principais autores:	Marco D. Rodríguez, Joshua A. Morris, Oliver J. Bardsley, Hugh R. Matthews, Christopher L.-H. Huang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-12-01
coleção:	Frontiers in Physiology
Assuntos:	skeletal muscle excitation–contraction coupling triad junction calcium microdomains Nernst–Planck equation electrodiffusion
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphys.2024.1468333/full
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