Health economic analysis of polygenic risk score use in primary prevention of coronary artery disease – A system dynamics model

Background: Primary prevention programs utilising traditional risk scores fail to identify all individuals who suffer acute cardiovascular events. We aimed to model the impact and cost effectiveness of incorporating a Polygenic risk scores (PRS) into the cardiovascular disease CVD primary prevention...

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Principais autores:	Stephen T. Vernon, Stuart Brentnall, Danielle J Currie, Cindy Peng, Michael P. Gray, Giordano Botta, Deo Mujwara, Stephen J. Nicholls, Stuart M. Grieve, Julie Redfern, Clara Chow, Jean-Frederic Levesque, Peter J. Meikle, Garry Jennings, Zanfina Ademi, Andrew Wilson, Gemma A. Figtree
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2024-06-01
Serija:	American Journal of Preventive Cardiology
Teme:	Health economics Polygenic risk score Coronary artery disease Cardiovascular disease
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2666667724000400
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