DNA mismatch repair in the context of chromatin
Abstract DNA mismatch repair (MMR) maintains replication fidelity by correcting mispaired nucleotides incorporated by DNA polymerases. Defects in MMR lead to cancers characterized by microsatellite instability. Recently, chromatin mechanisms that regulate MMR have been discovered, which sheds new li...
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| Автори: | , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2020-02-01
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| Серія: | Cell & Bioscience |
| Онлайн доступ: | https://doi.org/10.1186/s13578-020-0379-7 |
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