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Histidine-rich glycoprotein inhibits TNF-α–induced tube formation in human vascular endothelial cells

IntroductionTumor necrosis factor-α (TNF-α)-induced angiogenesis plays a critical role in tumor progression and metastasis, making it an important therapeutic target in cancer treatment. Suppressing angiogenesis can effectively limit tumor growth and metastasis. However, despite advancements in unde...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Omer Faruk Hatipoglu, Takashi Nishinaka, Kursat Oguz Yaykasli, Shuji Mori, Masahiro Watanabe, Takao Toyomura, Masahiro Nishibori, Satoshi Hirohata, Hidenori Wake, Hideo Takahashi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2025-03-01
Rangatū:Frontiers in Pharmacology
Ngā marau:
histidine-rich glycoprotein
tumor necrosis factor-α
integrin
tube formation
angiogenesis
factor erythroid 2-related factor 2
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fphar.2025.1561628/full
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