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Microwave-Assisted and Efficient Solvent-free Knoevenagel Condensation. A Sustainable Protocol Using Porous Calcium Hydroxyapatite as Catalyst

A sustainable Knoevenagel condensation of a series of aldehydes with malononitrile and ethyl cyanoacetate is described. The process is based on the combination of microwave activation and hydroxyapatite catalysis under solvent-free conditions. Products are obtained in and high yields after short rea...

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Principais autores: Rachid Benhida, Abdelaziz Laghzizil, Siham Mallouk, Khalid Bougrin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2010-02-01
coleção:Molecules
Assuntos:
Acesso em linha:http://www.mdpi.com/1420-3049/15/2/813/
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