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T3 and glucose increase expression of phosphoenolpyruvate carboxykinase (PCK1) leading to increased β-cell proliferation

Objectives: Thyroid hormone (T3) and high glucose concentrations are critical components of β-cell maturation and function. In the present study, we asked whether T3 and glucose signaling pathways coordinately regulate transcription of genes important for β-cell function and proliferation. Methods:...

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Xehetasun bibliografikoak
Egile Nagusiak: Liora S. Katz, Carmen Argmann, Luca Lambertini, Donald K. Scott
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2022-12-01
Saila:Molecular Metabolism
Gaiak:
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S2212877822002150
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