Salivary Gland Toxicity of PSMA-Targeted Radioligand Therapy with ¹⁷⁷Lu-PSMA and Combined ²²⁵Ac- and ¹⁷⁷Lu-Labeled PSMA Ligands (TANDEM-PRLT) in Advanced Prostate Cancer: A Single-Center Systematic Investigation

Purpose: PSMA-targeted radioligand therapy (PRLT) is a promising treatment option for patients with metastatic castration-resistant prostate cancer (mCRPC). However, a high uptake of the radiopharmaceutical in the salivary glands (SG) can lead to xerostomia and becomes dose-limiting for <sup>225</su...

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Autors principals:	Thomas Langbein, Harshad R. Kulkarni, Christiane Schuchardt, Dirk Mueller, Gerd Fabian Volk, Richard P. Baum
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-08-01
Col·lecció:	Diagnostics
Matèries:	PSMA radioligand therapy mCRPC salivary gland toxicity xerostomia
Accés en línia:	https://www.mdpi.com/2075-4418/12/8/1926
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