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Metabolite Identification of HIV-1 Capsid Modulators PF74 and 11L in Human Liver Microsomes

<b>PF74</b> and <b>11L</b>, as potent modulators of the HIV-1 capsid protein, have been demonstrated to act at both early and late stages in the HIV-1 life cycle. However, their clearance is high in human liver microsomes (HLMs). The main goal of this study was to clarify the metabolism of <b>PF74</...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Shujing Xu, Lin Sun, Dang Ding, Xujie Zhang, Xinyong Liu, Peng Zhan
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2022-08-01
Rangatū:Metabolites
Ngā marau:
Urunga tuihono:https://www.mdpi.com/2218-1989/12/8/752
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