Levels and instability of transthyretin and correlations with core biomarkers in Alzheimer’s disease

Abstract Transthyretin (TTR) has gained attention due to its implication in Alzheimer’s Disease (AD) by modulating amyloid-beta (Aβ) pathology. This study aimed to establish associations between TTR and key AD biomarkers, to enhance our understanding of the role of TTR in AD pathogenesis. We evaluat...

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Autors principals:	Tiago Gião, Miguel Tábuas-Pereira, Inês Baldeiras, Joana Saavedra, Alexandre Dias, Maria João Saraiva, Maria Rosário Almeida, Isabel Santana, Isabel Cardoso
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2026-03-01
Col·lecció:	Scientific Reports
Matèries:	Transthyretin Alzheimer’s disease Amyloid-β MCI Instability Blood-based biomarkers
Accés en línia:	https://doi.org/10.1038/s41598-026-41717-7
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