Cytotoxicity of Amino‐BODIPY Modulated via Conjugation with 2‐Phenyl‐3‐Hydroxy‐4(1H)‐Quinolinones

Abstract The combination of cytotoxic amino‐BODIPY dye and 2‐phenyl‐3‐hydroxy‐4(1H)‐quinolinone (3‐HQ) derivatives into one molecule gave rise to selective activity against lymphoblastic or myeloid leukemia and the simultaneous disappearance of the cytotoxicity against normal cells. Both species′ co...

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Autors principals:	Martin Porubský, Dr. Kristýna Vychodilová, Dr. David Milićević, Dr. Miloš Buděšinský, Jarmila Stanková, Dr. Petr Džubák, Dr. Marián Hajdúch, Prof. Jan Hlaváč
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley-VCH 2021-11-01
Col·lecció:	ChemistryOpen
Matèries:	amino-BODIPY dyes cytotoxic activity disulfide linkers glutathione hydroxyquinolinones
Accés en línia:	https://doi.org/10.1002/open.202100025
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