5-Demethylnobiletin mediates cell cycle arrest and apoptosis via the ERK1/2/AKT/STAT3 signaling pathways in glioblastoma cells

5-Demethylnobiletin is the active ingredient in citrus polymethoxyflavones that could inhibit the proliferation of several tumor cells. However, the anti-tumor effect of 5-Demethylnobiletin on glioblastoma and the underlying molecular mechanisms are remains unknown. In our study, 5-Demethylnobiletin...

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Auteurs principaux:	Xuehua Zhang, Leilei Zhao, Jinlong Xiao, Yudi Wang, Yunmeng Li, Chaoqun Zhu, He Zhang, Yurui Zhang, Xiao Zhu, Yucui Dong
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2023-04-01
Collection:	Frontiers in Oncology
Sujets:	glioblastoma 5-Demethylnobiletin cell cycle arrest cell apoptosis ERK1/2 AKT
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1143664/full
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