Functionalized methoxy quinoline derivatives: Experimental and in silico evaluation as new antiepileptic, anti-Alzheimer, antibacterial and antifungal drug candidates

The objective of this study was to assess the inhibitory effects of newly synthesized quinoline derivatives on human carbonic anhydrase I and II (hCA I and II), as well as acetylcholinesterase (AChE) enzymes, alongside their impact on various microorganisms. The synthesized compounds were assessed u...

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Hlavní autoři:	Bilge Çi̇ftci̇, Salih Ökten, Ümit Muhammet Koçyi̇ği̇t, Vildan Enisoğlu Atalay, Mehmet Ataş, Osman Çakmak
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-04-01
Edice:	European Journal of Medicinal Chemistry Reports
Témata:	Acetylcholinesterase enzyme inhibition Carbonic anhydrase enzyme inhibition Methoxyquinoline Quinoline
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2772417423000274
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