Interplay between Janus Kinase/Signal Transducer and Activator of Transcription Signaling Activated by Type I Interferons and Viral Antagonism

Interferons (IFNs), which were discovered a half century ago, are a group of secreted proteins that play key roles in innate immunity against viral infection. The major signaling pathway activated by IFNs is the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway, which...

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Autori principali:	Yuchen Nan, Chunyan Wu, Yan-Jin Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2017-12-01
Serie:	Frontiers in Immunology
Soggetti:	interferons Janus kinase/signal transducer and activator of transcription signaling Janus kinases signal transducer and activator of transcriptions viral antagonism viral attenuation
Accesso online:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01758/full
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