Distinct DNA methylation signatures associated with blood lipids as exposures or outcomes among survivors of childhood cancer: a report from the St. Jude lifetime cohort

Abstract Background DNA methylation (DNAm) plays an important role in lipid metabolism, however, no epigenome-wide association study (EWAS) of lipid levels has been conducted among childhood cancer survivors. Here, we performed EWAS analysis with longitudinally collected blood lipid data from surviv...

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Główni autorzy:	Qian Dong, Cheng Chen, Nan Song, Na Qin, Noel-Marie Plonski, Emily R. Finch, Kyla Shelton, John Easton, Heather Mulder, Emily Plyer, Geoffrey Neale, Emily Walker, Qian Li, I-Chan Huang, Jinghui Zhang, Hui Wang, Melissa M. Hudson, Leslie L. Robison, Kirsten K. Ness, Zhaoming Wang
Format:	Artigo
Język:	Inglês
Wydane:	BMC 2023-02-01
Seria:	Clinical Epigenetics
Hasła przedmiotowe:	DNA methylation Lipid levels Childhood cancer survivors EWAS African ancestry European ancestry
Dostęp online:	https://doi.org/10.1186/s13148-023-01447-3
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