MicroRNA High Throughput Loss-of-Function Screening Reveals an Oncogenic Role for miR-21-5p in Hodgkin Lymphoma

Background/Aims: Classical Hodgkin lymphoma (cHL) is among the most frequent lymphoma subtypes. The tumor cells originate from crippled germinal center (GC)-B cells that escaped from apoptosis. MicroRNAs (miRNAs) play important roles in B-cell maturation and aberrant expression of miRNAs contributes...

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Autors principals:	Ye Yuan, Fubiao Niu, Ilja M. Nolte, Jasper Koerts, Debora de Jong, Bea Rutgers, Jan Osinga, Maria Azkanaz, Martijn Terpstra, Leonid Bystrykh, Arjan Diepstra, Lydia Visser, Agnieszka Dzikiewicz-Krawczyk, Klaas Kok, Joost  Kluiver, Anke van den Berg
Format:	Artigo
Idioma:	Inglês
Publicat:	Cell Physiol Biochem Press GmbH & Co KG 2018-09-01
Col·lecció:	Cellular Physiology and Biochemistry
Matèries:	Classical Hodgkin lymphoma (cHL) High-throughput screen miR-21-5p Apoptosis BTG2 PELI1
Accés en línia:	https://www.karger.com/Article/FullText/492850
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