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Deciphering the Contributions of CRH Receptors in the Brain and Pituitary to Stress-Induced Inhibition of the Reproductive Axis

Based on pharmacological studies, corticotropin-releasing hormone (CRH) and its receptors play a leading role in the inhibition of the hypothalamic–pituitary–gonadal (HPG) axis during acute stress. To further study the effects of CRH receptor signaling on the HPG axis, we generated and/or employed m...

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Principais autores: Androniki Raftogianni, Lena C. Roth, Diego García-González, Thorsten Bus, Claudia Kühne, Hannah Monyer, Daniel J. Spergel, Jan M. Deussing, Valery Grinevich
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-08-01
coleção:Frontiers in Molecular Neuroscience
Assuntos:
stress
reproduction
CRH
CRH receptors
GnRH
GnRH neurons
Acesso em linha:https://www.frontiersin.org/article/10.3389/fnmol.2018.00305/full
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