Discovery and validation of programmed cell death–associated key biomarker genes in ischemic stroke via ssGSEA/WGCNA and LASSO–SVM-RFE

BackgroundIschemic stroke (IS) currently lacks well-characterized peripheral-blood biomarkers that capture early, pathway-level biology. Programmed cell death (PCD) pathways may shape post-stroke neuroinflammation and could yield clinically informative transcriptional signatures.MethodsPublic cohort...

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Hlavní autoři:	Qi Jia, Pengtao Zhang, Qianqian Liu, Enze Sang, Zhengwen Chen, Junjie Shao, Yuhao Ding, Faguang Bai, Qingfeng Huang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-07-01
Edice:	Frontiers in Molecular Biosciences
Témata:	biomarkers ischemic stroke machine learning programmed cell death ssGSEA WGCNA
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fmolb.2026.1844734/full
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