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Prospective identification of variables as outcomes for treatment (PIVOT): study protocol for a randomised, placebo-controlled trial of hydroxyurea for Ghanaian children and adults with haemoglobin SC disease

Abstract Background Haemoglobin SC (HbSC) is a common form of sickle cell disease (SCD), especially among individuals of West African ancestry. Persons with HbSC disease suffer from the same clinical complications and reduced quality of life that affect those with sickle cell anaemia (HbSS/Sβ0). Ret...

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Autores principales: Luke R. Smart, Catherine I. Segbefia, Teresa S. Latham, Susan E. Stuber, Kwesi N. Amissah-Arthur, Klenam Dzefi-Tettey, Adam C. Lane, Yvonne A. Dei-Adomakoh, Russell E. Ware
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2023-09-01
Colección:Trials
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Acceso en línea:https://doi.org/10.1186/s13063-023-07649-7
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