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Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells

<p>Abstract</p> <p>Background</p> <p>Translational control mediated by non-coding microRNAs (miRNAs) plays a key role in the mechanism of cellular resistance to anti-cancer drug treatment. Dihydrofolate reductase (DHFR) and thymidylate synthase (TYMS, TS) are two of the most important targets for an...

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Bibliografski detalji
Glavni autori: Formentini Andrea, Botchkina Galina, Titmus Matthew A, Wang Yuan, Song Bo, Kornmann Marko, Ju Jingfang
Format: Artigo
Jezik:Inglês
Izdano: BMC 2010-04-01
Serija:Molecular Cancer
Online pristup:http://www.molecular-cancer.com/content/9/1/96
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