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Population Pharmacokinetics of Intravenous Acyclovir in Oncologic Pediatric Patients

Background: Acyclovir represents the first-line prophylaxis and therapy for herpes virus infections. However, its pharmacokinetics in children exposes them to the risk of ineffective or toxic concentrations. The study was aimed at investigating the population pharmacokinetics (POP/PK) of intravenous...

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Hlavní autoři: Natalia Maximova, Daniela Nisticò, Giacomo Luci, Roberto Simeone, Elisa Piscianz, Ludovica Segat, Egidio Barbi, Antonello Di Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-04-01
Edice:Frontiers in Pharmacology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fphar.2022.865871/full
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