In-Host Flat-like Quasispecies: Characterization Methods and Clinical Implications

The repeated failure to treat patients chronically infected with hepatitis E (HEV) and C (HCV) viruses, despite the absence of resistance-associated substitutions (RAS), particularly in response to prolonged treatments with the mutagenic agents of HEV, suggests that quasispecies structure may play a...

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Hlavní autoři:	Josep Gregori, Sergi Colomer-Castell, Marta Ibañez-Lligoña, Damir Garcia-Cehic, Carolina Campos, Maria Buti, Mar Riveiro-Barciela, Cristina Andrés, Maria Piñana, Alejandra González-Sánchez, Francisco Rodriguez-Frias, Maria Francesca Cortese, David Tabernero, Ariadna Rando-Segura, Tomás Pumarola, Juan Ignacio Esteban, Andrés Antón, Josep Quer
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2024-05-01
Edice:	Microorganisms
Témata:	viral treatment failures resistance-associated mutations (RAS) mutagens enhanced fitness flat-like quasispecies near-flat
On-line přístup:	https://www.mdpi.com/2076-2607/12/5/1011
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