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Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases

Abstract BMP-1/tolloid-like proteinases (BTPs) are major players in tissue morphogenesis, growth and repair. They act by promoting the deposition of structural extracellular matrix proteins and by controlling the activity of matricellular proteins and TGF-β superfamily growth factors. They have also...

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Asıl Yazarlar: Sandrine Vadon-Le Goff, Agnès Tessier, Manon Napoli, Cindy Dieryckx, Julien Bauer, Mélissa Dussoyer, Priscillia Lagoutte, Célian Peyronnel, Lucie Essayan, Svenja Kleiser, Nicole Tueni, Emmanuel Bettler, Natacha Mariano, Elisabeth Errazuriz-Cerda, Carole Fruchart Gaillard, Florence Ruggiero, Christoph Becker-Pauly, Jean-Marc Allain, Leena Bruckner-Tuderman, Alexander Nyström, Catherine Moali
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Portfolio 2023-12-01
Seri Bilgileri:Nature Communications
Online Erişim:https://doi.org/10.1038/s41467-023-43401-0
Etiketler: Etiketle
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