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Structural diversity of Burkholderia pseudomallei lipopolysaccharides affects innate immune signaling.

Burkholderia pseudomallei (Bp) causes the disease melioidosis. The main cause of mortality in this disease is septic shock triggered by the host responding to lipopolysaccharide (LPS) components of the Gram-negative outer membrane. Bp LPS is thought to be a weak inducer of the host immune system. LP...

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Autori principali: Michael H Norris, Herbert P Schweizer, Apichai Tuanyok
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2017-04-01
Serie:PLoS Neglected Tropical Diseases
Accesso online:http://europepmc.org/articles/PMC5425228?pdf=render
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