Untargeted metabolomics reveals immune-metabolic signatures in established cases of rheumatoid arthritis

IntroductionRheumatoid arthritis (RA) is a complex progressive autoimmune disorder wherein chronic inflammation is tightly coupled to metabolic reprogramming. The known diagnostic markers are not sensitive and specific enough to reflect disease activity. Finding a metabolomics-based biomarker specif...

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Principais autores:	Afshan Masood, Reem Almalki, Abeer Malkawi, Maha Al Mogren, Amal Jaafar, Hicham Benabdelkamel, Assim A. Alfadda, Amina Fallata, Abdurhman S. Alarfaj, Mohamed Siaj, Anas M. Abdel Rahman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-02-01
Colecção:	Frontiers in Molecular Biosciences
Assuntos:	glycerophospholipids immune–metabolic dysregulation metabolomics N2-acetyl N6-methyllysine nucleic acids plasma biomarkers
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmolb.2026.1755542/full
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