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Sphingomyelin synthase-related protein is a regulator of serine palmitoyltransferase

Sphingomyelin synthase-related protein (SMSr) belongs to the SMS family; however, it cannot synthesize SM. We reported that SMSr is a phosphatidylethanolamine-specific phospholipase C, which is associated with metabolic dysfunction-associated fatty liver disease (MAFLD). However, the mechanism is un...

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Principais autores: Xiang Li, Zhiqiang Li, Yeun-po Chiang, Tilla Worgall, Tade Souaiaia, Xian-Cheng Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-11-01
coleção:Journal of Lipid Research
Assuntos:
Sphingomyelin Synthase Related Protein
Phosphatidylethanolamine-specific phospholipase C
Serine Palmitoyltransferase
Phosphatidylethanolamine
Sphingolipid biosynthesis
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0022227525001701
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