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DOK3 negatively regulates LPS responses and endotoxin tolerance.

Innate immune activation via Toll-like receptors (TLRs), although critical for host defense against infection, must be regulated to prevent sustained cell activation that can lead to cell death. Cells repeatedly stimulated with lipopolysaccharide (LPS) develop endotoxin tolerance making the cells hy...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Qisheng Peng, Jason L O'Loughlin, Mary Beth Humphrey
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2012-01-01
Rangatū:PLoS ONE
Urunga tuihono:http://europepmc.org/articles/PMC3384629?pdf=render
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