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Glucose and glutamine availability regulate HepG2 transcriptional responses to low oxygen [version 1; referees: 2 approved]

Background: Little is known about the impact of nutrients on cellular transcriptional responses, especially in face of environmental stressors such as oxygen deprivation. Hypoxia-inducible factors (HIF) coordinate the expression of genes essential for adaptation to oxygen-deprived environments. A se...

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Bibliografiske detaljer
Principais autores: Alvina G. Lai, Donall Forde, Wai Hoong Chang, Fang Yuan, Xiaodong Zhuang, Claudia Orbegozo Rubio, Chun-Xiao Song, Jane A. McKeating
Format: Artigo
Sprog:Inglês
Udgivet: Wellcome 2018-09-01
Serier:Wellcome Open Research
Online adgang:https://wellcomeopenresearch.org/articles/3-126/v1
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