Identifying CD19-targeted CAR-T cell immune pathways in an in vitro human immune mimetic cytokine release assay

CD19-targeted chimeric antigen receptor-modified T (CAR-T) cells have shown success in clinical studies, with several CD19 CAR-T cell products now having been approved for market use. However, this cell therapy can be associated with side effects such as cytokine release syndrome (CRS). Therefore, p...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Thuvan Dinh-Le, John Escobar, Louis Poisson, Karissa Adkins, Maria Jornet Culubret, Lukas Scheller, Jan van den Brulle, Michael Hudecek, Donald R. Drake III, Miriam Alb, Ernesto Luna
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Taylor & Francis Group 2024-12-01
سلاسل:	Journal of Immunotoxicology
الموضوعات:	CAR-T cells cytokines 3D co-culture T cell activation in vitro
الوصول للمادة أونلاين:	https://www.tandfonline.com/doi/10.1080/1547691X.2024.2378729
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!