Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2.
Malic enzyme 2 (ME2) is a mitochondrial enzyme that catalyzes the conversion of malate to pyruvate and CO2 and uses NAD as a cofactor. Higher expression of this enzyme correlates with the degree of cell de-differentiation. We found that ME2 is expressed in K562 erythroleukemia cells, in which a numb...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science (PLoS)
2010-09-01
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| Edice: | PLoS ONE |
| On-line přístup: | http://europepmc.org/articles/PMC2932743?pdf=render |
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