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Pan-neutralizing, germline-encoded antibodies against SARS-CoV-2: Addressing the long-term problem of escape variants

Despite the initially reported high efficacy of vaccines directed against ancestral SARS-CoV-2, repeated infections in both unvaccinated and vaccinated populations remain a major global health challenge. Because of mutation-mediated immune escape by variants-of-concern (VOC), approved neutralizing a...

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Hlavní autoři: Justin Mark Lunderberg, Sanjucta Dutta, Ai-Ris Y. Collier, Jeng-Shin Lee, Yen-Ming Hsu, Qiao Wang, Weina Zheng, Shushun Hao, Haohai Zhang, Lili Feng, Simon C. Robson, Wenda Gao, Stefan Riedel
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-10-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1032574/full
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