Basal Ganglia Neuromodulation Over Multiple Temporal and Structural Scales—Simulations of Direct Pathway MSNs Investigate the Fast Onset of Dopaminergic Effects and Predict the Role of Kv4.2

The basal ganglia are involved in the motivational and habitual control of motor and cognitive behaviors. Striatum, the largest basal ganglia input stage, integrates cortical and thalamic inputs in functionally segregated cortico-basal ganglia-thalamic loops, and in addition the basal ganglia output...

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Detalhes bibliográficos

Principais autores:	Robert Lindroos, Matthijs C. Dorst, Kai Du, Marko Filipović, Daniel Keller, Maya Ketzef, Alexander K. Kozlov, Arvind Kumar, Mikael Lindahl, Anu G. Nair, Juan Pérez-Fernández, Sten Grillner, Gilad Silberberg, Jeanette Hellgren Kotaleski
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-02-01
coleção:	Frontiers in Neural Circuits
Assuntos:	striatum medium spiny projection neurons dopamine simulations Kv4.2 subcellular signaling
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fncir.2018.00003/full
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