Long non-coding SINEUP RNA enhancing BDNF translation prevents dendritic atrophy following an Aβ-peptide challenge

Abstract In Alzheimer’s disease (AD), brain levels of Brain-derived neurotrophic factor (BDNF) are reduced. BDNF, a neurotrophin involved in neuronal development and plasticity, has a protective role against the cytotoxic effects of Aβ, a pathological hallmark of AD. Since therapeutic approaches to...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Marta Atzori, Elsa Fabbretti, Viviana Ciraci, Silvia Zucchelli, Carlotta Bon, Sanja Mikašinović, Gabriele Baj, Stefano Gustincich, Enrico Tongiorgi
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Springer 2026-03-01
Σειρά:	Cellular and Molecular Life Sciences
Θέματα:	Alzheimer’s diseases Neuronal atrophy Dendritic dystrophy Neuroprotection Long non-coding RNA Gene-therapy
Διαθέσιμο Online:	https://doi.org/10.1007/s00018-026-06175-4
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